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Astrazeneca, Oxford University says COVID-19 vaccine 62 to 90% effective depending on dosage

Results based on Phase 3 trial in United Kingdom, Brazil before trials in U.S.

After a Phase 3 trial, officials said a vaccine from Oxford University and Astrazeneca pharmaceutical company is up to 90% effective.

The results were based on trials in the United Kingdom and Brazil before the trials start in the United States.

The trial tested two different dosage strategies. When the vaccine was given as a half dose followed by a full dose at least a month later, it was 90% effective.

“We’re really excited both about these vaccines and their potential, as well as the mRNA vaccines where there’s been some data already reported by Pfizer and Moderna,” said Dr. Daniel Kaul with Michigan Medicine.

READ: FDA grants emergency use authorization for Regeneron’s COVID-19 antibody cocktail

Kaul said the University of Michigan has been enrolling patients in the trial for several weeks now. He said he doesn’t have concerns about speed with which the vaccine has been developed.

“Doing something fast and taking shortcuts are different things. In this case, it’s been it’s been done very quickly, but to my observation there really haven’t been any shortcuts,” he said.

The Oxford-Astrazeneca vaccine has some advantages over the Pfizer and Moderna vaccine. It can be stored in a refrigerator, making it easier to ship and distribute.

It is also significantly cheaper to produce, costing $3 to $4 per shot.

READ: Michigan’s ‘3-week pause’ COVID restrictions in effect: What to know

Astrazeneca said there were “no hospitalizations or severe cases of the disease” reported in participants receiving the vaccine.

Kaul said he is encouraged by the results so far and looks forward to see more data.

“While there’s a lot of controversy around vaccines, there really isn’t any controversy around vaccines in the medical community. They’ve been one of the most important interventions and have saved more human lives than perhaps anything but you know clean water and things like that,” he said.

READ: Continuous Michigan COVID-19 coverage

You can watch the full report in the video posted above.


About the Author
Frank McGeorge, MD headshot

Dr. McGeorge can be seen on Local 4 News helping Metro Detroiters with health concerns when he isn't helping save lives in the emergency room at Henry Ford Hospital.

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