The setup for two Christmas Day games means two games on Saturday in Week 16.

Six division matchups and Kirk Cousins' return to Minnesota highlight a lighter Week 14 schedule.

Sam Darnold’s second touchdown pass of the second half went to Aaron Jones for Minnesota’s first lead with 1:13 left, and the Vikings rallied from 13 points down to beat the Arizona Cardinals 23-22 for their fifth straight victory.

Jon Jones sent Stipe Miocic into retirement with a stunning back kick to the ribs and used a series of blows to the head in the third round to retain the UFC heavyweight championship in front of President-elect Donald Trump in the main event of UFC 309 at Madison Square Garden on Saturday night.

Emari Demercado ran 53 yards for a touchdown just before halftime, James Conner added 107 yards on the ground and the surging Arizona Cardinals put together a dominant 29-9 victory over the Chicago Bears on Sunday.

Kyler Murray drove the Cardinals into position for a game-winning field goal by Chad Ryland as time expired for the second straight week, and Arizona spoiled Tua Tagovailoa’s return from a concussion, beating the Miami Dolphins 28-27.

Lamar Jackson couldn’t have performed much better as a passer when he threw five TD passes, only five incompletions and no interceptions while throwing for 281 yards in a victory for Baltimore over Tampa Bay.

Kyler Murray ran for a 44-yard touchdown and led the Cardinals on a drive that set up Chad Ryland’s 32-yard field goal as time expired, and Arizona rallied for a 17-15 win over the Los Angeles Chargers.

Romeo Doubs returned from a one-game suspension and caught two of Jordan Love’s four touchdown passes in the Green Bay Packers’ 34-13 victory over the mistake-prone Arizona Cardinals.

Perhaps the only way the Oklahoma-Texas rivalry could have become even more intense happened when both joined the powerful Southeastern Conference in July.

Kyler Murray had a long touchdown run in the first quarter and rallied Arizona with two fourth-quarter scoring drives in the Cardinals’ 24-23 victory over the San Francisco 49ers on Sunday.

The days of NFL rookie quarterbacks waiting their turns before taking over teams is long gone.

Joe Flacco watched football from his couch last season before joining the Cleveland Browns in November, leading them to the playoffs and earning the AP Comeback Player of the Year award.

James Conner ran for a 2-yard touchdown with 32 seconds remaining, Kyler Murray threw three TD passes, and the Arizona Cardinals rallied from a 15-point deficit to stun Philadelphia 35-31 and disrupt the Eagles’ playoff path.

Christian McCaffrey scored three touchdowns, Charvarius Ward had two interceptions, including a pick-6, and the San Francisco 49ers clinched the NFC West while pushing their winning streak to six games with a 45-29 win over the Arizona Cardinals.

This year’s Heisman Trophy ceremony is an ode to the new era of college sports, transformed by the transfer portal and NIL.

Dillon Gabriel accounted for a school-record eight touchdowns to help No. 17 Oklahoma roll past West Virginia 59-20.

Quarterback Kyler Murray said he’s returning to the practice field on Wednesday for the Arizona Cardinals as he works to come back from a torn ACL in his right knee that he suffered last season.

Utah quarterback Cam Rising told a radio station in Salt Lake City that the knee injury he suffered during last season’s Rose Bowl damaged multiple ligaments and he is still hoping to play this season.

Patrick Mahomes saw his first extended action of the preseason, throwing for 105 yards and a touchdown, and the Kansas City Chiefs beat the Arizona Cardinals 38-10 on Saturday night in the second preseason game for both teams.

Arizona Cardinals quarterback Kyler Murray is working his way back to football relevancy following an underwhelming fourth season that was cut short by a torn ACL in his right knee last December.

The Arizona Cardinals have released three-time All-Pro wide receiver DeAndre Hopkins in a salary cap move made after they failed to find a trading partner in the offseason.

The 2024 NFL draft class could quickly transform losers into winners.

The Texans got two of the best players in the NFL draft in the first three picks.

The Arizona Cardinals and owner Michael Bidwill deny they are liable to front office executive Terry McDonough for any of the claims he made against the team in a demand for arbitration, and say his “erratic behavior eventually damaged his career.”.

Philadelphia Eagles quarterback Jalen Hurts is wealthier after getting his new contract.

The Arizona Cardinals have fired coach Kliff Kingsbury and parted ways with general manager Steve Keim after a dreadful season that saw constant unwanted headlines, a serious knee injury to star quarterback Kyler Murray and lots of losing.

The Denver Broncos are holding quarterback Russell Wilson out of this weekend's game against the Arizona Cardinals, even though he passed concussion protocol Friday.

Arizona Cardinals quarterback Kyler Murray has a torn ACL and will miss the remainder of the season.

Mac Jones threw for 235 yards, Raekwon McMillan had a crucial fumble return for a touchdown and the New England Patriots earned a 27-13 win on Monday night over the Arizona Cardinals, who lost starting quarterback Kyler Murray in the first quarter to a potentially serious knee injury.

Cardinals quarterback Kyler Murray was carted off the field during the team’s first offensive drive after a knee injury Monday night in Arizona’s game against the New England Patriots.

Jimmy Garoppolo threw four touchdown passes, including two each to Brandon Aiyuk and George Kittle, and the San Francisco 49ers won their third straight game by beating the Arizona Cardinals 38-10 in Mexico City.

Ron Rivera and Washington are making a habit of shocking undefeated teams.

There has already been two coaching changes halfway through the NFL season with Indianapolis firing Frank Reich this week four weeks after Carolina did the same to Matt Rhule.

Jalen Hurts and the undefeated Eagles are looking for the first 8-0 start in franchise history while the rest of Philadelphia is focused on beating another team from Houston.

Marco Wilson and Isaiah Simmons scored touchdowns on two pick-6s late in the first half and used that stunning change in momentum to lift the Arizona Cardinals over the New Orleans Saints 42-34.

Can we finally start Tony Pollard.

A pair of underachieving 2-4 teams face off on Thursday night when the Arizona Cardinals host the New Orleans Saints.

Carson Wentz takes enough hits on and off the field that short rest is just another obstacle.

Jalen Hurts ran for two touchdowns and the Philadelphia Eagles remained the NFL’s only unbeaten team, beating Arizona 20-17 on Sunday after Matt Ammendola’s late field-goal attempt for the Cardinals sailed wide right.

Tua Tagovailoa and the unbeaten Miami Dolphins are underdogs in Week 4.

Kyler Murray appears content to let things that happened in Vegas stay in Vegas.

Police in Las Vegas say they're investigating allegations that a fan struck Arizona Cardinals quarterback Kyler Murray amid celebrations of Arizona’s 29-23 overtime victory over the Raiders.

Byron Murphy Jr. scooped up Hunter Renfrow’s fumble and returned it 59 yards for a touchdown with 3:51 left in overtime and the Arizona Cardinals rallied from a 20-point deficit in the second half before running away with a 29-23 victory over the Las Vegas Raiders.

Preseason rest appeared to lead to a little bit of rust in Week 1 for several of the NFL’s top quarterbacks.

Patrick Mahomes threw for 360 yards and five touchdowns, lifting the Kansas City Chiefs to an impressive 44-21 road win over the Arizona Cardinals in the opener for both teams.

Rookie tight end Isaiah Likely caught eight passes for 100 yards and a touchdown and the Baltimore Ravens ran their preseason winning streak to 22 games, beating the Arizona Cardinals 24-17 on Sunday night.

The Arizona Cardinals are preparing for six games without star receiver DeAndre Hopkins.

Lamar Jackson’s contract negotiations are lingering into training camp, and the Baltimore quarterback says at a certain point, it could be time to put those talks aside.

The Arizona Cardinals have removed an addendum to quarterback Kyler Murray’s $230.5 million, five-year contract that mandated at least four hours of “independent study” during game weeks.

New Broncos quarterback Russell Wilson is in a hurry to turn Denver's fortunes around.

The Arizona Cardinals say they're not worried about quarterback Kyler Murray's game preparation habits.

Training camps opened across the NFL and the biggest offseason question remains unanswered.

Patrick Mahomes walked onto the practice field at Missouri Western on Sunday flanked by a flotilla of rookies and longshots, many of whom have long dreamed of making in a year what the Chiefs quarterback will make by the end of the day.

Kyler Murray has a low-key personality by nature.

Deshaun Watson reported to his first training camp with the Cleveland Browns not knowing how long he’ll be their starting quarterback.

Kyler Murray has agreed to a long-term contract that will keep the quarterback with the Arizona Cardinals through the 2028 season.

Jackson Nicklaus hit a grand slam, Jake Bennett pitched six strong innings and Oklahoma jumped on Texas A&M early in a 13-8 win in the College World Series opener.

Tom Brady earned the right to skip voluntary workouts a long time ago.

Arizona Cardinals three-time All-Pro receiver DeAndre Hopkins has been suspended six games for violating the NFL’s policy on performance-enhancing substances.

Luka Doncic had 33 points and 13 rebounds in his first home playoff game coming off a calf injury and the Dallas Mavericks routed the Utah Jazz 102-77 for a 3-2 lead in their first-round playoff series.

This year's quarterback class isn't as heralded as last year's or even next year's.

Mike Krzyzewski has already turned his attention to the postseason after losing his final home game at Duke.

This year's class of college quarterbacks isn't as strong as past years have been.

The Chargers’ Justin Herbert hit Baltimore’s Mark Andrews with two touchdown passes to leading the AFC to a 41-35 victory over the NFC in the return of the Pro Bowl.

Kyler Murray’s first NFL playoff start quickly turned into a nightmare.

Matthew Stafford passed for 202 yards and two touchdowns in his first playoff victory and the Los Angeles Rams roared out of the wild-card round with a 34-11 win over the Arizona Cardinals.

Kyler Murray has kept a low-key demeanor throughout his football career, staying with a “never too high, never too low” philosophy that’s allowed him to thrive from the high school level all the way through the NFL.

Safety Eric Weddle is coming out of retirement to rejoin the Los Angeles Rams for the playoffs.

Russell Wilson threw three touchdown passes, Rashaad Penny ran for 173 yards and a touchdown, and the Seattle Seahawks spoiled a shot at the NFC West title for the Arizona Cardinals by beating them 38-30 on Sunday.

The Associated Press will hand out its individual NFL awards on Feb. 10 at NFL Honors in Los Angeles.

Kyler Murray threw two touchdown passes to Antoine Wesley and the Arizona Cardinals held on to beat the Dallas Cowboys 25-22 in a matchup of playoff-bound teams.

Carson Wentz threw two touchdown passes, Jonathan Taylor ran for 108 yards and the banged-up Indianapolis Colts continued their late-season surge with a gritty 22-16 win over the Arizona Cardinals.

A week ago, the Detroit Lions looked as if they had finished their season early.

Kyler Murray had a shaky performance and that helped the Detroit Lions stun the Arizona Cardinals 30-12 on Sunday.

The Detroit Lions upset the Arizona Cardinals on Sunday at Ford Field -- and they did it in convincing fashion.

Matthew Stafford threw for 287 yards and three touchdowns, Cooper Kupp and Odell Beckham Jr. each caught a touchdown pass and the Los Angeles Rams held on for a 30-23 win over the Arizona Cardinals.

Kyler Murray threw for two touchdowns and ran for two more in his return from an ankle injury and the Arizona Cardinals beat the struggling Chicago Bears 33-22.

Seattle’s Adrian Peterson has moved into a tie with Jim Brown for 10th all-time in total career touchdowns.

Oklahoma has hired Clemson defensive coordinator Brent Venables as its head coach to replace Lincoln Riley.

The Arizona Cardinals, Green Bay Packers and the Tampa Bay Buccaneers have retained the top three spots in the latest AP Pro32 poll.

The Arizona Cardinals, playing once again without starting quarterback Kyler Murray and star wide receiver DeAndre Hopkins, returned to the top spot of the latest AP Pro32 poll.

Colt McCoy was outstanding filling in for Kyler Murray, throwing for 328 yards and two touchdowns, and the Arizona Cardinals beat the Seattle Seahawks 23-13.

Reigning Defensive Rookie of the Year Chase Young suffered a potentially serious right knee injury, putting a damper on Washington’s big win against Tom Brady and the Tampa Bay Buccaneers.

Cam Newton provided a flashback to his Superman days in his second debut with the Panthers He threw for one touchdown, ran for another and sparked Carolina to a 34-10 win over the Arizona Cardinals.

Despite being short-handed, the Arizona Cardinals returned to the top of the AP Pro32 poll after beating the San Francisco 49ers without quarterback Kyler Murray and wide receiver DeAndre Hopkins.

James Conner ran for two touchdowns and caught a 45-yard TD pass from backup quarterback Colt McCoy as the short-handed Arizona Cardinals beat the San Francisco 49ers 31-17.

Aaron Rodgers threw two touchdown passes, Randall Cobb caught both of them and the Green Bay Packers knocked off the previously unbeaten Arizona Cardinals 24-21 after Kyler Murray’s stunning late interception on Thursday night.

Tampa Bay is 6-1 for the first time in franchise history, and Las Vegas is 2-0 without Jon Gruden.

Kyler Murray threw four touchdown passes as the Arizona Cardinals remained the NFL’s only unbeaten team.

Cleveland Browns defensive end Myles Garrett is tackling quarterbacks on the field and burying them in his front yard.

The Arizona Cardinals and the Buffalo Bills are tied for the top spot in the latest AP Pro32 poll.

The Arizona Cardinals improved to 5-0 for the first time since 1974, riding a stellar defensive performance to a 17-10 win over the San Francisco 49ers on Sunday.

The Arizona Cardinals, the only unbeaten team remaining in the NFL, have climbed all the way to the top of the latest AP Pro32 poll.

The Arizona Cardinals extended their longest unbeaten start since 2012 with a 37-20 victory over the Los Angeles Rams.

Tom Brady is the NFL’s new all-time passing leader.

Byron Murphy intercepted two passes, including one he returned for a touchdown following a botched trick play, and the Arizona Cardinals rallied to beat the skidding Jacksonville Jaguars 31-19 on Sunday.

Kyler Murray threw for 400 yards and three touchdowns, and the Arizona Cardinals topped the Minnesota Vikings 34-33 after Greg Joseph missed a 37-yard field goal wide right in the final seconds.

The NFL has the first 14-11 halftime score in its 102 seasons.

Tom Brady and the Tampa Bay Buccaneers are on top of the first AP Pro32 poll of the season.