Moderna says its COVID-19 vaccine works in babies, toddlers and preschoolers.

Moderna is scaling back expectations for the number of COVID-19 vaccine deliveries it expects to make this year and the revenue it will record from them.

Warning of tough days ahead with surging COVID-19 infections, the director of the National Institutes of Health says the U.S. could decide in the next couple weeks whether to offer coronavirus booster shots to more Americans this fall.

Moderna President Dr. Stephen Hoge says his company is working on developing COVID-19 vaccine booster shots while also trying to harness the genetic code technology it helped pioneer to fight other diseases.

On Monday, Moderna joined Pfizer in submitting its vaccine for an emergency use authorization. But if a vaccine is authorized, will people be willing to get it? “We asked a national sample of older adults, aged 50-60, (about the) future COVID-19 vaccine and what their thoughts were,” U of M Dr. Preeti Malani said. Moderna COVID-19 vaccine moves step closer to public useModerna’s COVID-19 vaccine hit another major milestone, as the company is submitting its application for an emergency use authorization, starting the formal review process and moving a step closer to public use. “This is clearly the most important point prior to making the vaccine broadly available,” Moderna President Dr. Stephen Hoge said.

As of now, the restrictions are in place for three weeks -- from Wednesday (Nov. 18) through Dec. 8. The number of confirmed cases of the coronavirus (COVID-19) in Michigan has risen to 251,813 as of Saturday, including 7,994 deaths, state officials report. On Friday, Michigan reported 244,741 total cases and 7,929 deaths. The state shattered its previous high for single-day totals of COVID-19 cases Friday, reporting a record breaking 8,516 new cases. Additionally, the state reported a total of 138,862 COVID-19 recoveries SaturdayNew COVID-19 cases and deaths continue to rise in Michigan.

Moderna said its vaccine appears to be 94.5% effective, according to preliminary data from an ongoing study. Moderna’s vaccine is being studied in 30,000 volunteers who received either the real thing or a dummy shot. Earlier this year, Fauci said he would be happy with a COVID-19 vaccine that was 60% effective. Moderna’s vaccine also starts off frozen, but the company said Monday it can be thawed and kept in a regular refrigerator for 30 days, easing that concern. Both Moderna's shots and the Pfizer-BioNTech candidate are so-called mRNA vaccines, a brand-new technology.

Kim Reynolds has dropped her opposition to a statewide mandate for mask use to combat the spread of the coronavirus. The mandate applies only when people are within six feet of others for 15 minutes and they aren’t members of their households. ______NEW BRUNSWICK, N.J. — Johnson & Johnson has begun a new late-stage trial of its experimental COVID-19 vaccine, this time on a two-dose regimen. Gavin Newsom said he was pulling the “emergency brake” Monday on the state’s efforts to reopen its economy as coronavirus cases surge more dramatically than during a summer spike. ___BERLIN — German Chancellor Angela Merkel said on Monday the number of new coronavirus cases is flattening following two weeks of new restrictions, but it’s too early to tell whether more will be necessary.