Since the middle of November, the entire region has returned to levels similar to those seen in October.
Governors have used the declining numbers to justify their divergent approaches to fighting the pandemic, even jousting at times.
As the pandemic crept into communities across the Midwest, more people had loved ones, friends or acquaintances fall ill or die.
Many health experts warned that the region was ripe for widespread infections, especially as the weather cooled and people gathered inside, making it easier for the coronavirus to spread.
Other experts say some pockets of people, such as those who work in meatpacking plants where infections were widespread, had experienced such high rates of infections that the virus has slowed.